Hepatitis E virus is highly prevalent in the Danish pig population

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Hepatitis E virus is highly prevalent in the Danish pig population. / Breum, Solvej; Hjulsager, Charlotte K.; de Deus, Nilsa; Segalés, Joaquim; Larsen, Lars E.

I: Veterinary Microbiology, Bind 146, Nr. 1-2, 20.11.2010, s. 144-149.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Breum, S, Hjulsager, CK, de Deus, N, Segalés, J & Larsen, LE 2010, 'Hepatitis E virus is highly prevalent in the Danish pig population', Veterinary Microbiology, bind 146, nr. 1-2, s. 144-149. https://doi.org/10.1016/j.vetmic.2010.05.002

APA

Breum, S., Hjulsager, C. K., de Deus, N., Segalés, J., & Larsen, L. E. (2010). Hepatitis E virus is highly prevalent in the Danish pig population. Veterinary Microbiology, 146(1-2), 144-149. https://doi.org/10.1016/j.vetmic.2010.05.002

Vancouver

Breum S, Hjulsager CK, de Deus N, Segalés J, Larsen LE. Hepatitis E virus is highly prevalent in the Danish pig population. Veterinary Microbiology. 2010 nov. 20;146(1-2):144-149. https://doi.org/10.1016/j.vetmic.2010.05.002

Author

Breum, Solvej ; Hjulsager, Charlotte K. ; de Deus, Nilsa ; Segalés, Joaquim ; Larsen, Lars E. / Hepatitis E virus is highly prevalent in the Danish pig population. I: Veterinary Microbiology. 2010 ; Bind 146, Nr. 1-2. s. 144-149.

Bibtex

@article{32c5d54969534cb68a5b52afc61440f5,
title = "Hepatitis E virus is highly prevalent in the Danish pig population",
abstract = "The objective of this study was to examine the prevalence of Hepatitis E virus (HEV) in the Danish pig population. Faecal samples from 97 pigs, 1-5 months of age were analysed for HEV RNA by a new PriProET real time RT-PCR assay. In addition, serum samples from 71 sow herds were screened for the presence of anti-HEV IgG antibodies by ELISA. The genotype of the detected HEV positive samples was estimated based on the melting temperature obtained by the PriProET real time RT-PCR assay. The HEV prevalence of faecal samples was 55.0% and 49.5% for herds and animals, respectively. A HEV IgG prevalence of 91.5% was found for the sow herds which correspond to 73.2% of the sows. The PriProET assay indicated that all HEV positive samples belonged to genotype 3 or 4, which is consistent with the observation of genotype 3 as dominant in European pigs. This is the first study showing that HEV is highly prevalent in the Danish pig population. The abundant presence of HEV in Danish pigs and the known high similarity between HEV isolates from pigs and humans support previous reports indicating possible zoonotic transmission of HEV.",
keywords = "Epidemiology, Genotype 3, Hepatitis E virus (HEV), Swine, Zoonosis",
author = "Solvej Breum and Hjulsager, {Charlotte K.} and {de Deus}, Nilsa and Joaquim Segal{\'e}s and Larsen, {Lars E.}",
year = "2010",
month = nov,
day = "20",
doi = "10.1016/j.vetmic.2010.05.002",
language = "English",
volume = "146",
pages = "144--149",
journal = "Veterinary Microbiology",
issn = "0378-1135",
publisher = "Elsevier",
number = "1-2",

}

RIS

TY - JOUR

T1 - Hepatitis E virus is highly prevalent in the Danish pig population

AU - Breum, Solvej

AU - Hjulsager, Charlotte K.

AU - de Deus, Nilsa

AU - Segalés, Joaquim

AU - Larsen, Lars E.

PY - 2010/11/20

Y1 - 2010/11/20

N2 - The objective of this study was to examine the prevalence of Hepatitis E virus (HEV) in the Danish pig population. Faecal samples from 97 pigs, 1-5 months of age were analysed for HEV RNA by a new PriProET real time RT-PCR assay. In addition, serum samples from 71 sow herds were screened for the presence of anti-HEV IgG antibodies by ELISA. The genotype of the detected HEV positive samples was estimated based on the melting temperature obtained by the PriProET real time RT-PCR assay. The HEV prevalence of faecal samples was 55.0% and 49.5% for herds and animals, respectively. A HEV IgG prevalence of 91.5% was found for the sow herds which correspond to 73.2% of the sows. The PriProET assay indicated that all HEV positive samples belonged to genotype 3 or 4, which is consistent with the observation of genotype 3 as dominant in European pigs. This is the first study showing that HEV is highly prevalent in the Danish pig population. The abundant presence of HEV in Danish pigs and the known high similarity between HEV isolates from pigs and humans support previous reports indicating possible zoonotic transmission of HEV.

AB - The objective of this study was to examine the prevalence of Hepatitis E virus (HEV) in the Danish pig population. Faecal samples from 97 pigs, 1-5 months of age were analysed for HEV RNA by a new PriProET real time RT-PCR assay. In addition, serum samples from 71 sow herds were screened for the presence of anti-HEV IgG antibodies by ELISA. The genotype of the detected HEV positive samples was estimated based on the melting temperature obtained by the PriProET real time RT-PCR assay. The HEV prevalence of faecal samples was 55.0% and 49.5% for herds and animals, respectively. A HEV IgG prevalence of 91.5% was found for the sow herds which correspond to 73.2% of the sows. The PriProET assay indicated that all HEV positive samples belonged to genotype 3 or 4, which is consistent with the observation of genotype 3 as dominant in European pigs. This is the first study showing that HEV is highly prevalent in the Danish pig population. The abundant presence of HEV in Danish pigs and the known high similarity between HEV isolates from pigs and humans support previous reports indicating possible zoonotic transmission of HEV.

KW - Epidemiology

KW - Genotype 3

KW - Hepatitis E virus (HEV)

KW - Swine

KW - Zoonosis

UR - http://www.scopus.com/inward/record.url?scp=78049282306&partnerID=8YFLogxK

U2 - 10.1016/j.vetmic.2010.05.002

DO - 10.1016/j.vetmic.2010.05.002

M3 - Journal article

C2 - 20554125

AN - SCOPUS:78049282306

VL - 146

SP - 144

EP - 149

JO - Veterinary Microbiology

JF - Veterinary Microbiology

SN - 0378-1135

IS - 1-2

ER -

ID: 247398542