Identification and molecular characterization of Staphylococcus aureus and multi-drug resistant MRSA from monkey faeces in China
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Identification and molecular characterization of Staphylococcus aureus and multi-drug resistant MRSA from monkey faeces in China. / Li, Yang; Tang, Yuanyue; Ren, Jingwei; Huang, Jinlin; Li, Qiuchun; Ingmer, Hanne; Jiao, Xinan.
I: Transboundary and Emerging Diseases, Bind 67, Nr. 3, 2020, s. 1382-1387.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Identification and molecular characterization of Staphylococcus aureus and multi-drug resistant MRSA from monkey faeces in China
AU - Li, Yang
AU - Tang, Yuanyue
AU - Ren, Jingwei
AU - Huang, Jinlin
AU - Li, Qiuchun
AU - Ingmer, Hanne
AU - Jiao, Xinan
PY - 2020
Y1 - 2020
N2 - Staphylococcus aureus is a commensal bacterium and an important opportunistic pathogen in humans and animals. The increase in multi-drug resistant (MDR) strains of S. aureus is a growing concern due to their impact on animal health and potential for zoonotic transmission. Increasing evidence has shown that MRSA could be transmitted by faeces. The present study determined the prevalence, antibiotic resistance profile and genotypic characteristics of S. aureus isolated from monkey faecal samples in China. Thirty-eight out of 145 (26.21%) macaque faecal samples were S. aureus positive, which eight (5.5%) isolates were identified as MRSA. Antimicrobial susceptibility tests showed that most of the S. aureus isolates were resistant to tetracycline (TE, 44.74%), followed by penicillin (P, 21.05%), cefoxitin (FOX, 21.05%) and ciprofloxacin (CIP, 18.42%). The predominant spa types were t13638 (44.74%) and t189 (13.16%), which are reported to be closely associated with human infections in China. All MRSA isolates belonged to the SCCmecV type, which six of MRSA isolates were ST3268, while the other two isolates belonged to ST4981. This study for the first time describes the prevalence of S. aureus and MRSA in monkey faeces in China, indicating that faeces could be a potential factor of transmitting S. aureus between humans and monkeys.
AB - Staphylococcus aureus is a commensal bacterium and an important opportunistic pathogen in humans and animals. The increase in multi-drug resistant (MDR) strains of S. aureus is a growing concern due to their impact on animal health and potential for zoonotic transmission. Increasing evidence has shown that MRSA could be transmitted by faeces. The present study determined the prevalence, antibiotic resistance profile and genotypic characteristics of S. aureus isolated from monkey faecal samples in China. Thirty-eight out of 145 (26.21%) macaque faecal samples were S. aureus positive, which eight (5.5%) isolates were identified as MRSA. Antimicrobial susceptibility tests showed that most of the S. aureus isolates were resistant to tetracycline (TE, 44.74%), followed by penicillin (P, 21.05%), cefoxitin (FOX, 21.05%) and ciprofloxacin (CIP, 18.42%). The predominant spa types were t13638 (44.74%) and t189 (13.16%), which are reported to be closely associated with human infections in China. All MRSA isolates belonged to the SCCmecV type, which six of MRSA isolates were ST3268, while the other two isolates belonged to ST4981. This study for the first time describes the prevalence of S. aureus and MRSA in monkey faeces in China, indicating that faeces could be a potential factor of transmitting S. aureus between humans and monkeys.
KW - antimicrobial resistance
KW - monkeys
KW - MRSA
KW - MSSA
KW - Staphylococcus aureus
U2 - 10.1111/tbed.13450
DO - 10.1111/tbed.13450
M3 - Journal article
C2 - 31838770
AN - SCOPUS:85077367834
VL - 67
SP - 1382
EP - 1387
JO - Transboundary and Emerging Diseases
JF - Transboundary and Emerging Diseases
SN - 1865-1674
IS - 3
ER -
ID: 234276296