Investigating the Crime Scene—Molecular Signatures in Inflammatory Bowel Disease

Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt

Standard

Investigating the Crime Scene—Molecular Signatures in Inflammatory Bowel Disease. / Andersen, Vibeke; Bennike, Tue B.; Bang, Corinna; Rioux, John D.; Hébert-Milette, Isabelle; Sato, Toshiro; Hansen, Axel K.; Nielsen, Ole H.

I: International Journal of Molecular Sciences, Bind 24, Nr. 13, 11217, 2023.

Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt

Harvard

Andersen, V, Bennike, TB, Bang, C, Rioux, JD, Hébert-Milette, I, Sato, T, Hansen, AK & Nielsen, OH 2023, 'Investigating the Crime Scene—Molecular Signatures in Inflammatory Bowel Disease', International Journal of Molecular Sciences, bind 24, nr. 13, 11217. https://doi.org/10.3390/ijms241311217

APA

Andersen, V., Bennike, T. B., Bang, C., Rioux, J. D., Hébert-Milette, I., Sato, T., Hansen, A. K., & Nielsen, O. H. (2023). Investigating the Crime Scene—Molecular Signatures in Inflammatory Bowel Disease. International Journal of Molecular Sciences, 24(13), [11217]. https://doi.org/10.3390/ijms241311217

Vancouver

Andersen V, Bennike TB, Bang C, Rioux JD, Hébert-Milette I, Sato T o.a. Investigating the Crime Scene—Molecular Signatures in Inflammatory Bowel Disease. International Journal of Molecular Sciences. 2023;24(13). 11217. https://doi.org/10.3390/ijms241311217

Author

Andersen, Vibeke ; Bennike, Tue B. ; Bang, Corinna ; Rioux, John D. ; Hébert-Milette, Isabelle ; Sato, Toshiro ; Hansen, Axel K. ; Nielsen, Ole H. / Investigating the Crime Scene—Molecular Signatures in Inflammatory Bowel Disease. I: International Journal of Molecular Sciences. 2023 ; Bind 24, Nr. 13.

Bibtex

@article{7bcbfcf129214b56a341a974dca26d3a,
title = "Investigating the Crime Scene—Molecular Signatures in Inflammatory Bowel Disease",
abstract = "Inflammatory bowel diseases (IBD) are without cure and troublesome to manage because of the considerable diversity between patients and the lack of reliable biomarkers. Several studies have demonstrated that diet, gut microbiota, genetics and other patient factors are essential for disease occurrence and progression. Understanding the link between these factors is crucial for identifying molecular signatures that identify biomarkers to advance the management of IBD. Recent technological breakthroughs and data integration have fuelled the intensity of this research. This research demonstrates that the effect of diet depends on patient factors and gut microbial activity. It also identifies a range of potential biomarkers for IBD management, including mucosa-derived cytokines, gasdermins and neutrophil extracellular traps, all of which need further evaluation before clinical translation. This review provides an update on cutting-edge research in IBD that aims to improve disease management and patient quality of life.",
keywords = "biomarkers, Crohn{\textquoteright}s disease, gut microbiota, intestinal barrier, personalised medicine, ulcerative colitis",
author = "Vibeke Andersen and Bennike, {Tue B.} and Corinna Bang and Rioux, {John D.} and Isabelle H{\'e}bert-Milette and Toshiro Sato and Hansen, {Axel K.} and Nielsen, {Ole H.}",
note = "Publisher Copyright: {\textcopyright} 2023 by the authors.",
year = "2023",
doi = "10.3390/ijms241311217",
language = "English",
volume = "24",
journal = "International Journal of Molecular Sciences (Online)",
issn = "1661-6596",
publisher = "MDPI AG",
number = "13",

}

RIS

TY - JOUR

T1 - Investigating the Crime Scene—Molecular Signatures in Inflammatory Bowel Disease

AU - Andersen, Vibeke

AU - Bennike, Tue B.

AU - Bang, Corinna

AU - Rioux, John D.

AU - Hébert-Milette, Isabelle

AU - Sato, Toshiro

AU - Hansen, Axel K.

AU - Nielsen, Ole H.

N1 - Publisher Copyright: © 2023 by the authors.

PY - 2023

Y1 - 2023

N2 - Inflammatory bowel diseases (IBD) are without cure and troublesome to manage because of the considerable diversity between patients and the lack of reliable biomarkers. Several studies have demonstrated that diet, gut microbiota, genetics and other patient factors are essential for disease occurrence and progression. Understanding the link between these factors is crucial for identifying molecular signatures that identify biomarkers to advance the management of IBD. Recent technological breakthroughs and data integration have fuelled the intensity of this research. This research demonstrates that the effect of diet depends on patient factors and gut microbial activity. It also identifies a range of potential biomarkers for IBD management, including mucosa-derived cytokines, gasdermins and neutrophil extracellular traps, all of which need further evaluation before clinical translation. This review provides an update on cutting-edge research in IBD that aims to improve disease management and patient quality of life.

AB - Inflammatory bowel diseases (IBD) are without cure and troublesome to manage because of the considerable diversity between patients and the lack of reliable biomarkers. Several studies have demonstrated that diet, gut microbiota, genetics and other patient factors are essential for disease occurrence and progression. Understanding the link between these factors is crucial for identifying molecular signatures that identify biomarkers to advance the management of IBD. Recent technological breakthroughs and data integration have fuelled the intensity of this research. This research demonstrates that the effect of diet depends on patient factors and gut microbial activity. It also identifies a range of potential biomarkers for IBD management, including mucosa-derived cytokines, gasdermins and neutrophil extracellular traps, all of which need further evaluation before clinical translation. This review provides an update on cutting-edge research in IBD that aims to improve disease management and patient quality of life.

KW - biomarkers

KW - Crohn’s disease

KW - gut microbiota

KW - intestinal barrier

KW - personalised medicine

KW - ulcerative colitis

U2 - 10.3390/ijms241311217

DO - 10.3390/ijms241311217

M3 - Review

C2 - 37446397

AN - SCOPUS:85164846413

VL - 24

JO - International Journal of Molecular Sciences (Online)

JF - International Journal of Molecular Sciences (Online)

SN - 1661-6596

IS - 13

M1 - 11217

ER -

ID: 362696872