Premature delivery reduces intestinal cytoskeleton, metabolism, and stress response proteins in newborn formula-fed pigs

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Standard

Premature delivery reduces intestinal cytoskeleton, metabolism, and stress response proteins in newborn formula-fed pigs. / Jiang, Pingping; Wan, Jennifer Man-Fan; Cilieborg, Malene Skovsted; Sit, Wai-Hung; Sangild, Per Torp.

I: Journal of Pediatric Gastroenterology and Nutrition, Bind 56, Nr. 6, 2013, s. 615-622.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Jiang, P, Wan, JM-F, Cilieborg, MS, Sit, W-H & Sangild, PT 2013, 'Premature delivery reduces intestinal cytoskeleton, metabolism, and stress response proteins in newborn formula-fed pigs', Journal of Pediatric Gastroenterology and Nutrition, bind 56, nr. 6, s. 615-622. https://doi.org/10.1097/MPG.0b013e318288cf71

APA

Jiang, P., Wan, J. M-F., Cilieborg, M. S., Sit, W-H., & Sangild, P. T. (2013). Premature delivery reduces intestinal cytoskeleton, metabolism, and stress response proteins in newborn formula-fed pigs. Journal of Pediatric Gastroenterology and Nutrition, 56(6), 615-622. https://doi.org/10.1097/MPG.0b013e318288cf71

Vancouver

Jiang P, Wan JM-F, Cilieborg MS, Sit W-H, Sangild PT. Premature delivery reduces intestinal cytoskeleton, metabolism, and stress response proteins in newborn formula-fed pigs. Journal of Pediatric Gastroenterology and Nutrition. 2013;56(6):615-622. https://doi.org/10.1097/MPG.0b013e318288cf71

Author

Jiang, Pingping ; Wan, Jennifer Man-Fan ; Cilieborg, Malene Skovsted ; Sit, Wai-Hung ; Sangild, Per Torp. / Premature delivery reduces intestinal cytoskeleton, metabolism, and stress response proteins in newborn formula-fed pigs. I: Journal of Pediatric Gastroenterology and Nutrition. 2013 ; Bind 56, Nr. 6. s. 615-622.

Bibtex

@article{d970307313754c2b829e315c34830631,
title = "Premature delivery reduces intestinal cytoskeleton, metabolism, and stress response proteins in newborn formula-fed pigs",
abstract = "OBJECTIVE:: Preterm infants often show intolerance to the first enteral feeds, and the structural and functional basis of this intolerance remains unclear. We hypothesized that preterm and term neonates show similar gut trophic responses to feeding, but different expression of intestinal functional proteins, thus helping to explain why preterm neonates are more susceptible to feeding-induced disorders such as necrotizing enterocolitis (NEC). METHODS:: Incidence of feeding-induced NEC, intestinal mass and brush-border enzyme activities, and the intestinal proteome in preterm caesarean-delivered pigs were compared with the corresponding values in pigs delivered spontaneously at term. RESULTS:: For both preterm and term pigs, mucosal mass and maltase activity increased (+50-100%), while lactase decreased (-50%), relative to values at birth. Only preterm pigs were highly NEC-sensitive (30 vs. 0% in term pigs, P¿",
author = "Pingping Jiang and Wan, {Jennifer Man-Fan} and Cilieborg, {Malene Skovsted} and Wai-Hung Sit and Sangild, {Per Torp}",
note = "CURIS 2013 NEXS 050",
year = "2013",
doi = "10.1097/MPG.0b013e318288cf71",
language = "English",
volume = "56",
pages = "615--622",
journal = "Journal of Pediatric Gastroenterology and Nutrition",
issn = "0277-2116",
publisher = "Lippincott Williams & Wilkins",
number = "6",

}

RIS

TY - JOUR

T1 - Premature delivery reduces intestinal cytoskeleton, metabolism, and stress response proteins in newborn formula-fed pigs

AU - Jiang, Pingping

AU - Wan, Jennifer Man-Fan

AU - Cilieborg, Malene Skovsted

AU - Sit, Wai-Hung

AU - Sangild, Per Torp

N1 - CURIS 2013 NEXS 050

PY - 2013

Y1 - 2013

N2 - OBJECTIVE:: Preterm infants often show intolerance to the first enteral feeds, and the structural and functional basis of this intolerance remains unclear. We hypothesized that preterm and term neonates show similar gut trophic responses to feeding, but different expression of intestinal functional proteins, thus helping to explain why preterm neonates are more susceptible to feeding-induced disorders such as necrotizing enterocolitis (NEC). METHODS:: Incidence of feeding-induced NEC, intestinal mass and brush-border enzyme activities, and the intestinal proteome in preterm caesarean-delivered pigs were compared with the corresponding values in pigs delivered spontaneously at term. RESULTS:: For both preterm and term pigs, mucosal mass and maltase activity increased (+50-100%), while lactase decreased (-50%), relative to values at birth. Only preterm pigs were highly NEC-sensitive (30 vs. 0% in term pigs, P¿

AB - OBJECTIVE:: Preterm infants often show intolerance to the first enteral feeds, and the structural and functional basis of this intolerance remains unclear. We hypothesized that preterm and term neonates show similar gut trophic responses to feeding, but different expression of intestinal functional proteins, thus helping to explain why preterm neonates are more susceptible to feeding-induced disorders such as necrotizing enterocolitis (NEC). METHODS:: Incidence of feeding-induced NEC, intestinal mass and brush-border enzyme activities, and the intestinal proteome in preterm caesarean-delivered pigs were compared with the corresponding values in pigs delivered spontaneously at term. RESULTS:: For both preterm and term pigs, mucosal mass and maltase activity increased (+50-100%), while lactase decreased (-50%), relative to values at birth. Only preterm pigs were highly NEC-sensitive (30 vs. 0% in term pigs, P¿

U2 - 10.1097/MPG.0b013e318288cf71

DO - 10.1097/MPG.0b013e318288cf71

M3 - Journal article

C2 - 23364244

VL - 56

SP - 615

EP - 622

JO - Journal of Pediatric Gastroenterology and Nutrition

JF - Journal of Pediatric Gastroenterology and Nutrition

SN - 0277-2116

IS - 6

ER -

ID: 44706553