Recently introduced qacA/B genes in Staphylococcus epidermidis do not increase chlorhexidine MIC/MBC
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Standard
Recently introduced qacA/B genes in Staphylococcus epidermidis do not increase chlorhexidine MIC/MBC. / Skovgaard, Sissel; Larsen, Marianne Halberg; Nielsen, Lene Nørby; Skov, Robert Leo; Wong, Christian; Westh, Henrik T.; Ingmer, Hanne.
I: The Journal of antimicrobial chemotherapy, Bind 68, Nr. 10, 2013, s. 2226-2233.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Recently introduced qacA/B genes in Staphylococcus epidermidis do not increase chlorhexidine MIC/MBC
AU - Skovgaard, Sissel
AU - Larsen, Marianne Halberg
AU - Nielsen, Lene Nørby
AU - Skov, Robert Leo
AU - Wong, Christian
AU - Westh, Henrik T.
AU - Ingmer, Hanne
PY - 2013
Y1 - 2013
N2 - Chlorhexidine is used as a disinfectant to prevent surgical infections. Recently, studies have indicated that chlorhexidine usage has selected methicillin-resistant Staphylococcus aureus strains that are tolerant to chlorhexidine and that this may be related to the presence of the qacA/B-encoded efflux pumps. Here, we evaluated if high-level exposure to chlorhexidine selects for tolerant colonizing Staphylococcus epidermidis and we addressed the consequences of long-term exposure to chlorhexidine.
AB - Chlorhexidine is used as a disinfectant to prevent surgical infections. Recently, studies have indicated that chlorhexidine usage has selected methicillin-resistant Staphylococcus aureus strains that are tolerant to chlorhexidine and that this may be related to the presence of the qacA/B-encoded efflux pumps. Here, we evaluated if high-level exposure to chlorhexidine selects for tolerant colonizing Staphylococcus epidermidis and we addressed the consequences of long-term exposure to chlorhexidine.
U2 - 10.1093/jac/dkt182
DO - 10.1093/jac/dkt182
M3 - Journal article
C2 - 23739538
VL - 68
SP - 2226
EP - 2233
JO - Journal of Antimicrobial Chemotherapy
JF - Journal of Antimicrobial Chemotherapy
SN - 0305-7453
IS - 10
ER -
ID: 99349527