Renal enzyme activities in experimental ochratoxin a-induced porcine nephropathy: Diagnostic potential of phosphoenolpyruvate carboxyk1nase and gamma-glutamyl transpeptidase activity

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Standard

Renal enzyme activities in experimental ochratoxin a-induced porcine nephropathy : Diagnostic potential of phosphoenolpyruvate carboxyk1nase and gamma-glutamyl transpeptidase activity. / Krogh, Palle; Gyrd-Hansen, Nils; Hatd, Benedicte; Larsen, Steen; Nielsen, Jens Peter; Smith, Mogens; Ivanoff, Chris; Meisner, Herman.

I: Journal of Toxicology and Environmental Health, Bind 23, Nr. 1, 01.1988, s. 1-14.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Krogh, P, Gyrd-Hansen, N, Hatd, B, Larsen, S, Nielsen, JP, Smith, M, Ivanoff, C & Meisner, H 1988, 'Renal enzyme activities in experimental ochratoxin a-induced porcine nephropathy: Diagnostic potential of phosphoenolpyruvate carboxyk1nase and gamma-glutamyl transpeptidase activity', Journal of Toxicology and Environmental Health, bind 23, nr. 1, s. 1-14. https://doi.org/10.1080/15287398809531092

APA

Krogh, P., Gyrd-Hansen, N., Hatd, B., Larsen, S., Nielsen, J. P., Smith, M., Ivanoff, C., & Meisner, H. (1988). Renal enzyme activities in experimental ochratoxin a-induced porcine nephropathy: Diagnostic potential of phosphoenolpyruvate carboxyk1nase and gamma-glutamyl transpeptidase activity. Journal of Toxicology and Environmental Health, 23(1), 1-14. https://doi.org/10.1080/15287398809531092

Vancouver

Krogh P, Gyrd-Hansen N, Hatd B, Larsen S, Nielsen JP, Smith M o.a. Renal enzyme activities in experimental ochratoxin a-induced porcine nephropathy: Diagnostic potential of phosphoenolpyruvate carboxyk1nase and gamma-glutamyl transpeptidase activity. Journal of Toxicology and Environmental Health. 1988 jan.;23(1):1-14. https://doi.org/10.1080/15287398809531092

Author

Krogh, Palle ; Gyrd-Hansen, Nils ; Hatd, Benedicte ; Larsen, Steen ; Nielsen, Jens Peter ; Smith, Mogens ; Ivanoff, Chris ; Meisner, Herman. / Renal enzyme activities in experimental ochratoxin a-induced porcine nephropathy : Diagnostic potential of phosphoenolpyruvate carboxyk1nase and gamma-glutamyl transpeptidase activity. I: Journal of Toxicology and Environmental Health. 1988 ; Bind 23, Nr. 1. s. 1-14.

Bibtex

@article{dcea184286564262a1158a662c52699e,
title = "Renal enzyme activities in experimental ochratoxin a-induced porcine nephropathy: Diagnostic potential of phosphoenolpyruvate carboxyk1nase and gamma-glutamyl transpeptidase activity",
abstract = "Enzyme activities have been measured in needle biopsies from kidneys of pigs fed 1 ppm or 0.2 ppm of ochratoxin A for 1-5 wks. After feeding 1 ppm toxin for 1 wk, the activity of cytosolic phosphoenolpyruvate carboxykinase (PEPCK) was decreased by 40% and remained inhibited until the termination of the experiment (5 wk). The activity of gamma-glutamyl transpeptidase, a brush-border enzyme found in the proximal tubules, was reduced to a similar degree and remained inhibited. The activities of hexokinase, a cytosolic enzyme of general distribution in the nephron, and phosphate-dependent.",
author = "Palle Krogh and Nils Gyrd-Hansen and Benedicte Hatd and Steen Larsen and Nielsen, {Jens Peter} and Mogens Smith and Chris Ivanoff and Herman Meisner",
note = "Funding Information: This researchwas supported in part by National Institutes of Health grant AM 27987.We wish thank Helge Cydesen for assistance in the statistical analysis. Requests for reprints should be sent to Palle Krogh, Department of Microbiology, Royal Den-College, Juliane Mariesvej 30, DK-2100 Copenhagen, Denmark.",
year = "1988",
month = jan,
doi = "10.1080/15287398809531092",
language = "English",
volume = "23",
pages = "1--14",
journal = "Journal of Toxicology and Environmental Health",
issn = "0098-4108",
publisher = "Taylor & Francis",
number = "1",

}

RIS

TY - JOUR

T1 - Renal enzyme activities in experimental ochratoxin a-induced porcine nephropathy

T2 - Diagnostic potential of phosphoenolpyruvate carboxyk1nase and gamma-glutamyl transpeptidase activity

AU - Krogh, Palle

AU - Gyrd-Hansen, Nils

AU - Hatd, Benedicte

AU - Larsen, Steen

AU - Nielsen, Jens Peter

AU - Smith, Mogens

AU - Ivanoff, Chris

AU - Meisner, Herman

N1 - Funding Information: This researchwas supported in part by National Institutes of Health grant AM 27987.We wish thank Helge Cydesen for assistance in the statistical analysis. Requests for reprints should be sent to Palle Krogh, Department of Microbiology, Royal Den-College, Juliane Mariesvej 30, DK-2100 Copenhagen, Denmark.

PY - 1988/1

Y1 - 1988/1

N2 - Enzyme activities have been measured in needle biopsies from kidneys of pigs fed 1 ppm or 0.2 ppm of ochratoxin A for 1-5 wks. After feeding 1 ppm toxin for 1 wk, the activity of cytosolic phosphoenolpyruvate carboxykinase (PEPCK) was decreased by 40% and remained inhibited until the termination of the experiment (5 wk). The activity of gamma-glutamyl transpeptidase, a brush-border enzyme found in the proximal tubules, was reduced to a similar degree and remained inhibited. The activities of hexokinase, a cytosolic enzyme of general distribution in the nephron, and phosphate-dependent.

AB - Enzyme activities have been measured in needle biopsies from kidneys of pigs fed 1 ppm or 0.2 ppm of ochratoxin A for 1-5 wks. After feeding 1 ppm toxin for 1 wk, the activity of cytosolic phosphoenolpyruvate carboxykinase (PEPCK) was decreased by 40% and remained inhibited until the termination of the experiment (5 wk). The activity of gamma-glutamyl transpeptidase, a brush-border enzyme found in the proximal tubules, was reduced to a similar degree and remained inhibited. The activities of hexokinase, a cytosolic enzyme of general distribution in the nephron, and phosphate-dependent.

UR - http://www.scopus.com/inward/record.url?scp=0023852753&partnerID=8YFLogxK

U2 - 10.1080/15287398809531092

DO - 10.1080/15287398809531092

M3 - Journal article

C2 - 2891856

AN - SCOPUS:0023852753

VL - 23

SP - 1

EP - 14

JO - Journal of Toxicology and Environmental Health

JF - Journal of Toxicology and Environmental Health

SN - 0098-4108

IS - 1

ER -

ID: 285717697