Serum amyloid A isoforms in serum and synovial fluid from spontaneously diseased dogs with joint diseases or other conditions

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Serum amyloid A isoforms in serum and synovial fluid from spontaneously diseased dogs with joint diseases or other conditions. / Kjelgaard-Hansen, Mads Jens; Christensen, Michelle B.; Lee, Marcel Huisung; Jensen, Asger Lundorff; Jacobsen, Stine.

I: Veterinary Immunology and Immunopathology, Bind 117, Nr. 3-4, 2007, s. 296-301.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Kjelgaard-Hansen, MJ, Christensen, MB, Lee, MH, Jensen, AL & Jacobsen, S 2007, 'Serum amyloid A isoforms in serum and synovial fluid from spontaneously diseased dogs with joint diseases or other conditions', Veterinary Immunology and Immunopathology, bind 117, nr. 3-4, s. 296-301. https://doi.org/10.1016/j.vetimm.2007.03.008

APA

Kjelgaard-Hansen, M. J., Christensen, M. B., Lee, M. H., Jensen, A. L., & Jacobsen, S. (2007). Serum amyloid A isoforms in serum and synovial fluid from spontaneously diseased dogs with joint diseases or other conditions. Veterinary Immunology and Immunopathology, 117(3-4), 296-301. https://doi.org/10.1016/j.vetimm.2007.03.008

Vancouver

Kjelgaard-Hansen MJ, Christensen MB, Lee MH, Jensen AL, Jacobsen S. Serum amyloid A isoforms in serum and synovial fluid from spontaneously diseased dogs with joint diseases or other conditions. Veterinary Immunology and Immunopathology. 2007;117(3-4):296-301. https://doi.org/10.1016/j.vetimm.2007.03.008

Author

Kjelgaard-Hansen, Mads Jens ; Christensen, Michelle B. ; Lee, Marcel Huisung ; Jensen, Asger Lundorff ; Jacobsen, Stine. / Serum amyloid A isoforms in serum and synovial fluid from spontaneously diseased dogs with joint diseases or other conditions. I: Veterinary Immunology and Immunopathology. 2007 ; Bind 117, Nr. 3-4. s. 296-301.

Bibtex

@article{9957ddb0a1c311ddb6ae000ea68e967b,
title = "Serum amyloid A isoforms in serum and synovial fluid from spontaneously diseased dogs with joint diseases or other conditions",
abstract = "Serum amyloid A (SAA) is a major acute phase protein in dogs. However, knowledge of qualitative properties of canine SAA and extent of its synthesis in extrahepatic tissues is limited. The aim of the study was to investigate expression of different SAA isoforms in serum and synovial fluid in samples obtained from dogs (n = 16) suffering from different inflammatory or non-inflammatory conditions, which were either related or unrelated to joints. Expression of SAA isoforms was visualized by denaturing isoelectric focusing and Western blotting. Serum amyloid A was present in serum from all dogs with systemic inflammatory activity, and up to four major isoforms with apparent isoelectric points between 6.1 and 7.9 were identified. In synovial fluid from inflamed joints one or more highly alkaline SAA isoforms (with apparent isoelectric points above 9.3) were identified, with data suggesting local production of these isoforms in the canine inflamed joint.",
keywords = "Former LIFE faculty, Acute phase proteins, Arthritis, Canine, Serum amyloid A, Isoforms, Isoelectric focusing",
author = "Kjelgaard-Hansen, {Mads Jens} and Christensen, {Michelle B.} and Lee, {Marcel Huisung} and Jensen, {Asger Lundorff} and Stine Jacobsen",
year = "2007",
doi = "10.1016/j.vetimm.2007.03.008",
language = "English",
volume = "117",
pages = "296--301",
journal = "Veterinary Immunology and Immunopathology",
issn = "0165-2427",
publisher = "Elsevier",
number = "3-4",

}

RIS

TY - JOUR

T1 - Serum amyloid A isoforms in serum and synovial fluid from spontaneously diseased dogs with joint diseases or other conditions

AU - Kjelgaard-Hansen, Mads Jens

AU - Christensen, Michelle B.

AU - Lee, Marcel Huisung

AU - Jensen, Asger Lundorff

AU - Jacobsen, Stine

PY - 2007

Y1 - 2007

N2 - Serum amyloid A (SAA) is a major acute phase protein in dogs. However, knowledge of qualitative properties of canine SAA and extent of its synthesis in extrahepatic tissues is limited. The aim of the study was to investigate expression of different SAA isoforms in serum and synovial fluid in samples obtained from dogs (n = 16) suffering from different inflammatory or non-inflammatory conditions, which were either related or unrelated to joints. Expression of SAA isoforms was visualized by denaturing isoelectric focusing and Western blotting. Serum amyloid A was present in serum from all dogs with systemic inflammatory activity, and up to four major isoforms with apparent isoelectric points between 6.1 and 7.9 were identified. In synovial fluid from inflamed joints one or more highly alkaline SAA isoforms (with apparent isoelectric points above 9.3) were identified, with data suggesting local production of these isoforms in the canine inflamed joint.

AB - Serum amyloid A (SAA) is a major acute phase protein in dogs. However, knowledge of qualitative properties of canine SAA and extent of its synthesis in extrahepatic tissues is limited. The aim of the study was to investigate expression of different SAA isoforms in serum and synovial fluid in samples obtained from dogs (n = 16) suffering from different inflammatory or non-inflammatory conditions, which were either related or unrelated to joints. Expression of SAA isoforms was visualized by denaturing isoelectric focusing and Western blotting. Serum amyloid A was present in serum from all dogs with systemic inflammatory activity, and up to four major isoforms with apparent isoelectric points between 6.1 and 7.9 were identified. In synovial fluid from inflamed joints one or more highly alkaline SAA isoforms (with apparent isoelectric points above 9.3) were identified, with data suggesting local production of these isoforms in the canine inflamed joint.

KW - Former LIFE faculty

KW - Acute phase proteins

KW - Arthritis

KW - Canine

KW - Serum amyloid A

KW - Isoforms

KW - Isoelectric focusing

U2 - 10.1016/j.vetimm.2007.03.008

DO - 10.1016/j.vetimm.2007.03.008

M3 - Journal article

C2 - 17451811

VL - 117

SP - 296

EP - 301

JO - Veterinary Immunology and Immunopathology

JF - Veterinary Immunology and Immunopathology

SN - 0165-2427

IS - 3-4

ER -

ID: 8098089