TY - JOUR

T1 - Suspected zoonotic transmission of rotavirus group A in Danish adults

AU - Midgley, S. E.

AU - Hjulsager, C. K.

AU - Larsen, L. E.

AU - Falkenhorst, G.

AU - Böttiger, B.

PY - 2012/6

Y1 - 2012/6

N2 - Group A rotaviruses infect humans and a variety of animals. In July 2006 a rare rotavirus strain with G8P[14] specificity was identified in the stool samples of two adult patients with diarrheoa, who lived in the same geographical area in Denmark. Nucleotide sequences of the VP7, VP4, VP6, and NSP4 genes of the identified strains were identical. Phylogenetic analyses showed that both Danish G8P[14] strains clustered with rotaviruses of animal, mainly, bovine and caprine, origin. The high genetic relatedness to animal rotaviruses and the atypical epidemiological features suggest that these human G8P[14] strains were acquired through direct zoonotic transmission events.

AB - Group A rotaviruses infect humans and a variety of animals. In July 2006 a rare rotavirus strain with G8P[14] specificity was identified in the stool samples of two adult patients with diarrheoa, who lived in the same geographical area in Denmark. Nucleotide sequences of the VP7, VP4, VP6, and NSP4 genes of the identified strains were identical. Phylogenetic analyses showed that both Danish G8P[14] strains clustered with rotaviruses of animal, mainly, bovine and caprine, origin. The high genetic relatedness to animal rotaviruses and the atypical epidemiological features suggest that these human G8P[14] strains were acquired through direct zoonotic transmission events.

KW - Rotavirus

KW - zoonoses

UR - http://www.scopus.com/inward/record.url?scp=84860806740&partnerID=8YFLogxK

U2 - 10.1017/S0950268811001981

DO - 10.1017/S0950268811001981

M3 - Journal article

C2 - 21943834

AN - SCOPUS:84860806740

VL - 140

SP - 1013

EP - 1017

JO - Epidemiology and Infection

JF - Epidemiology and Infection

SN - 0950-2688

IS - 6

ER -