Transforming growth factor-beta. En potent multifunktionel voekstfaktor for normale og maligne celler

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Standard

Transforming growth factor-beta. En potent multifunktionel voekstfaktor for normale og maligne celler. / Nørgaard, P; Damstrup, L; Spang-Thomsen, M; Poulsen, H S.

I: Ugeskrift for læger, Bind 154, Nr. 49, 1992, s. 3494-8.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Nørgaard, P, Damstrup, L, Spang-Thomsen, M & Poulsen, HS 1992, 'Transforming growth factor-beta. En potent multifunktionel voekstfaktor for normale og maligne celler', Ugeskrift for læger, bind 154, nr. 49, s. 3494-8.

APA

Nørgaard, P., Damstrup, L., Spang-Thomsen, M., & Poulsen, H. S. (1992). Transforming growth factor-beta. En potent multifunktionel voekstfaktor for normale og maligne celler. Ugeskrift for læger, 154(49), 3494-8.

Vancouver

Nørgaard P, Damstrup L, Spang-Thomsen M, Poulsen HS. Transforming growth factor-beta. En potent multifunktionel voekstfaktor for normale og maligne celler. Ugeskrift for læger. 1992;154(49):3494-8.

Author

Nørgaard, P ; Damstrup, L ; Spang-Thomsen, M ; Poulsen, H S. / Transforming growth factor-beta. En potent multifunktionel voekstfaktor for normale og maligne celler. I: Ugeskrift for læger. 1992 ; Bind 154, Nr. 49. s. 3494-8.

Bibtex

@article{93d2e520654e11de8bc9000ea68e967b,
title = "Transforming growth factor-beta. En potent multifunktionel voekstfaktor for normale og maligne celler",
abstract = "The polypeptide growth factor transforming growth factor-beta (TGF-beta) is a multifunctional regulator of basic cellular functions: proliferation, differentiation, cell adhesion and interactions with the extracellular matrix. TGF-beta is part of a regulatory network of which our knowledge is still incomplete, together with other substances such as steroid hormones, oncogene products and integrins. Five isoforms for TGF-beta and five different TGF-beta receptors have been described. TGF-beta exhibits an antiproliferative effect in vitro and in vivo on many cells of epthelial, myeloid, lymphoid and mesenchymal origin together with a growth-stimulating effect on various cells like endothelial cells and epidermal keratinocytes. Production of TGF-beta and receptors for TGF-beta has been found in many cell types, both normal and malignant. Nevertheless the amount of in vivo data is too limited to identify possibilities for therapeutic intervention in the physiological and patophysiological functions of TGF-beta. Udgivelsesdato: 1992-Nov-30",
author = "P N{\o}rgaard and L Damstrup and M Spang-Thomsen and Poulsen, {H S}",
note = "Keywords: Breast Neoplasms; Cell Adhesion; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Female; Humans; Lung Neoplasms; Receptors, Cell Surface; Transforming Growth Factor beta",
year = "1992",
language = "Dansk",
volume = "154",
pages = "3494--8",
journal = "Ugeskrift for Laeger",
issn = "0041-5782",
publisher = "Almindelige Danske Laegeforening",
number = "49",

}

RIS

TY - JOUR

T1 - Transforming growth factor-beta. En potent multifunktionel voekstfaktor for normale og maligne celler

AU - Nørgaard, P

AU - Damstrup, L

AU - Spang-Thomsen, M

AU - Poulsen, H S

N1 - Keywords: Breast Neoplasms; Cell Adhesion; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Female; Humans; Lung Neoplasms; Receptors, Cell Surface; Transforming Growth Factor beta

PY - 1992

Y1 - 1992

N2 - The polypeptide growth factor transforming growth factor-beta (TGF-beta) is a multifunctional regulator of basic cellular functions: proliferation, differentiation, cell adhesion and interactions with the extracellular matrix. TGF-beta is part of a regulatory network of which our knowledge is still incomplete, together with other substances such as steroid hormones, oncogene products and integrins. Five isoforms for TGF-beta and five different TGF-beta receptors have been described. TGF-beta exhibits an antiproliferative effect in vitro and in vivo on many cells of epthelial, myeloid, lymphoid and mesenchymal origin together with a growth-stimulating effect on various cells like endothelial cells and epidermal keratinocytes. Production of TGF-beta and receptors for TGF-beta has been found in many cell types, both normal and malignant. Nevertheless the amount of in vivo data is too limited to identify possibilities for therapeutic intervention in the physiological and patophysiological functions of TGF-beta. Udgivelsesdato: 1992-Nov-30

AB - The polypeptide growth factor transforming growth factor-beta (TGF-beta) is a multifunctional regulator of basic cellular functions: proliferation, differentiation, cell adhesion and interactions with the extracellular matrix. TGF-beta is part of a regulatory network of which our knowledge is still incomplete, together with other substances such as steroid hormones, oncogene products and integrins. Five isoforms for TGF-beta and five different TGF-beta receptors have been described. TGF-beta exhibits an antiproliferative effect in vitro and in vivo on many cells of epthelial, myeloid, lymphoid and mesenchymal origin together with a growth-stimulating effect on various cells like endothelial cells and epidermal keratinocytes. Production of TGF-beta and receptors for TGF-beta has been found in many cell types, both normal and malignant. Nevertheless the amount of in vivo data is too limited to identify possibilities for therapeutic intervention in the physiological and patophysiological functions of TGF-beta. Udgivelsesdato: 1992-Nov-30

M3 - Tidsskriftartikel

C2 - 1334294

VL - 154

SP - 3494

EP - 3498

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

SN - 0041-5782

IS - 49

ER -

ID: 12870846