Antibiotic Resistance and the MRSA Problem

Research output: Contribution to journal › Journal article › Research › peer-review

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Antibiotic Resistance and the MRSA Problem. / Vestergaard, Martin; Frees, Dorte; Ingmer, Hanne.

In: Microbiology Spectrum, Vol. 7, No. 2, 2019.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Vestergaard, M, Frees, D & Ingmer, H 2019, 'Antibiotic Resistance and the MRSA Problem', Microbiology Spectrum, vol. 7, no. 2. https://doi.org/10.1128/microbiolspec.GPP3-0057-2018

APA

Vestergaard, M., Frees, D., & Ingmer, H. (2019). Antibiotic Resistance and the MRSA Problem. Microbiology Spectrum, 7(2). https://doi.org/10.1128/microbiolspec.GPP3-0057-2018

Vancouver

Vestergaard M, Frees D, Ingmer H. Antibiotic Resistance and the MRSA Problem. Microbiology Spectrum. 2019;7(2). https://doi.org/10.1128/microbiolspec.GPP3-0057-2018

Author

Vestergaard, Martin ; Frees, Dorte ; Ingmer, Hanne. / Antibiotic Resistance and the MRSA Problem. In: Microbiology Spectrum. 2019 ; Vol. 7, No. 2.

Bibtex

@article{2a17f7a0e6e942749b6abf3a006ec98f,
title = "Antibiotic Resistance and the MRSA Problem",
abstract = "Staphylococcus aureus is capable of becoming resistant to all classes of antibiotics clinically available and resistance can develop through de novo mutations in chromosomal genes or through acquisition of horizontally transferred resistance determinants. This review covers the most important antibiotics available for treatment of S. aureus infections and a special emphasis is dedicated to the current knowledge of the wide variety of resistance mechanisms that S. aureus employ to withstand antibiotics. Since resistance development has been inevitable for all currently available antibiotics, new therapies are continuously under development. Besides development of new small molecules affecting cell viability, alternative approaches including anti-virulence and bacteriophage therapeutics are being investigated and may become important tools to combat staphylococcal infections in the future.",
author = "Martin Vestergaard and Dorte Frees and Hanne Ingmer",
year = "2019",
doi = "10.1128/microbiolspec.GPP3-0057-2018",
language = "English",
volume = "7",
journal = "Microbiology spectrum",
issn = "2165-0497",
publisher = "American Society for Microbiology",
number = "2",

}

RIS

TY - JOUR

T1 - Antibiotic Resistance and the MRSA Problem

AU - Vestergaard, Martin

AU - Frees, Dorte

AU - Ingmer, Hanne

PY - 2019

Y1 - 2019

N2 - Staphylococcus aureus is capable of becoming resistant to all classes of antibiotics clinically available and resistance can develop through de novo mutations in chromosomal genes or through acquisition of horizontally transferred resistance determinants. This review covers the most important antibiotics available for treatment of S. aureus infections and a special emphasis is dedicated to the current knowledge of the wide variety of resistance mechanisms that S. aureus employ to withstand antibiotics. Since resistance development has been inevitable for all currently available antibiotics, new therapies are continuously under development. Besides development of new small molecules affecting cell viability, alternative approaches including anti-virulence and bacteriophage therapeutics are being investigated and may become important tools to combat staphylococcal infections in the future.

AB - Staphylococcus aureus is capable of becoming resistant to all classes of antibiotics clinically available and resistance can develop through de novo mutations in chromosomal genes or through acquisition of horizontally transferred resistance determinants. This review covers the most important antibiotics available for treatment of S. aureus infections and a special emphasis is dedicated to the current knowledge of the wide variety of resistance mechanisms that S. aureus employ to withstand antibiotics. Since resistance development has been inevitable for all currently available antibiotics, new therapies are continuously under development. Besides development of new small molecules affecting cell viability, alternative approaches including anti-virulence and bacteriophage therapeutics are being investigated and may become important tools to combat staphylococcal infections in the future.

U2 - 10.1128/microbiolspec.GPP3-0057-2018

DO - 10.1128/microbiolspec.GPP3-0057-2018

M3 - Journal article

C2 - 30900543

AN - SCOPUS:85063637795

VL - 7

JO - Microbiology spectrum

JF - Microbiology spectrum

SN - 2165-0497

IS - 2

ER -

ID: 216931373