Pathobiological Sciences

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  1. 2017
  2. Published

    Human embryonic stem cell derived cardiomyocytes self-arrange with areas of different subtypes during differentiation

    Vestergaard, M. L., Grubb, Søren, Rasmussen, K. K., Anderson-Jenkins, Z. L., Grunnet-Lauridsen, K., Callø, Kirstine, Clausen, C., Christensen, Søren Tvorup, Møllgård, Kjeld & tcg964, tcg964, 1 Nov 2017, In: Stem Cells and Development. 26, 21, p. 1566-1577 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Functional characterization of malaria parasites deficient in the K+ channel Kch2

    Ellekvist, P., Mlambo, G., Kumar, N. & Klærke, Dan Arne, Nov 2017, In: Biochemical and Biophysical Research Communications. 493, 1, p. 690-696 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Genomic study and medical subject headings enrichment analysis of early pregnancy rate and antral follicle numbers in Nelore heifers

    Oliveira Júnior, G. A., Perez, B. C., Cole, J. B., Santana, M. H. A., Silveira, J., Mazzoni, G., Ventura, R. V., Santana, M. L., Kadarmideen, H. N., Garrick, D. J. & Ferraz, J. B. S., Nov 2017, In: Journal of Animal Science. 95, 11, p. 4796-4812 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Differential expression and co-expression gene networks reveal candidate biomarkers of boar taint in non-castrated pigs

    Drag, Markus Hodal, Skinkyté-Juskiené, R., Do, D. N., Kogelman, L. & Kadarmideen, H. N., 22 Sep 2017, In: Scientific Reports. 7, 18 p., 12205.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Molecular cloning and functional expression of the K+ channel KV7.1 and the regulatory subunit KCNE1 from equine myocardium: [Inkl. corrigendum]

    Pedersen, P. J., Thomsen, K. B., Flak, J. B., Tejada, M. D. L. A., Hauser, Frank, Trachsel, D. S., Buhl, Rikke, Kalbfleisch, T., DePriest, M. S., MacLeod, J. N., Callø, Kirstine & Klærke, Dan Arne, Aug 2017, In: Research in Veterinary Science. 113, p. 79-86 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Oxytocin injections in the postpartal period affect mammary tight junctions in sows

    Farmer, C., Lessard, M., Knight, C. H. & Quesnel, H., Aug 2017, In: Journal of Animal Science. 95, 8, p. 3532-3539 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Potential Regulator and Causal Genes for Boar Taint in Pigs from genome-transcriptome (eQTL) mapping analyses

    Drag, Markus Hodal, Hansen, M. B. & Kadarmideen, H. N., 21 Jul 2017.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  9. Published

    RNA-Guided Activation of Pluripotency Genes in Human Fibroblasts

    Xiong, K., Zhou, Y., Blichfeld, K. A., Hyttel, P., Bolund, L., Freude, Kristine & Luo, Y., Jun 2017, In: Cellular Reprogramming. 19, 3, p. 189-198 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    T-type Ca2+ channels and autoregulation of local blood flow

    Jensen, Lars Jørn, Nielsen, Morten Schak, Salomonsson, M. & Sorensen, Charlotte Mehlin, 4 May 2017, In: Channels (Austin). 11, 3, p. 183-195

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Editorial: Hypothetically speaking

    Knight, C. H., May 2017, In: Journal of Dairy Research. 84, 2, p. 117-118 2 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  12. Published

    FOXO1, PXK, PYCARD and SAMD9L are differentially expressed by fibroblast-like cells in equine synovial membrane compared to joint capsule

    Thomsen, L. N., Thomsen, Preben Dybdahl, Downing, A., Talbot, R. & Berg, Lise Charlotte, Apr 2017, In: B M C Veterinary Research. 13, 8 p., 106.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Early discharge following birth: What characterises mothers and newborns?

    Nilsson, I. M. S., Kronborg, H., Knight, C. H. & Strandberg-Larsen, Katrine, Mar 2017, In: Sexual & Reproductive HealthCare. 11, p. 60-68

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Short communication: Staphylococcus aureus infection modulates expression of drug transporters and inflammatory biomarkers in mouse mammary gland

    Oskarsson, A., Yagdiran, Y., Nazemi, S., Tallkvist, J. & Knight, C. H., Mar 2017, In: Journal of Dairy Science. 100, 3, p. 2375-2380

    Research output: Contribution to journal › Letter › Research › peer-review

  15. Published

    Toward Development of Pluripotent Porcine Stem Cells by Road Mapping Early Embryonic Development

    Petkov, S., Freude, Kristine, Mashayekhi-Nezamabadi, K., Hyttel, P. & Hall, Vanessa Jane, Mar 2017, Animal Models and Human Reproduction: Cell and Molecular Approaches with Reference to Human Reproduction. Schatten, H. & Constantinescu, G. M. (eds.). Wiley-Blackwell, p. 485-508 24 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  16. Published

    Ventricular repolarization time, location of pacing stimulus and current pulse amplitude conspire to determine arrhythmogenicity in mice

    Speerschneider, T., Grubb, Søren, Olesen, Søren-Peter, Callø, Kirstine & Thomsen, Morten Bækgaard, 9 Feb 2017, In: Acta Physiologica. 219, 3, p. 662-670 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Editorial: The Hannah research Institute

    Knight, C. H., Feb 2017, In: Journal of Dairy Research. 84, 1, p. 1-2 2 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  18. Published

    A viral metagenomic approach on a nonmetagenomic experiment: Mining next generation sequencing datasets from pig DNA identified several porcine parvoviruses for a retrospective evaluation of viral infections

    Bovo, S., Mazzoni, G., Ribani, A., Utzeri, V. J., Bertolini, F., Schiavo, G. & Fontanesi, L., 2017, In: PLOS ONE. 12, 6, 17 p., e0179462.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Anatomical and Molecular insight into the developing entorhinal cortex in a large mammalian species, the pig.

    Liu, Y., Peralvo Vidal, Juan Miguel, Thomsen, Preben Dybdahl, Møllgård, Kjeld, Kirkeby, Agnete & Hall, Vanessa Jane, 2017.

    Research output: Contribution to conference › Conference abstract for conference › Research

  20. Published

    Androgen Insensitivity Syndrome in a Family of Warmblood Horses Caused by a 25-bp Deletion of the DNA-Binding Domain of the Androgen Receptor Gene

    Eastman Welsford, G., Munk, R., Villagómez, D. A. F., Hyttel, P., Allan King, W. & Revay, T., 2017, In: Sexual Development. 11, 1, p. 40-45 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Application of integrative genomics and systems biology to conventional and in vitro reproductive traits in cattle

    Mazzoni, G., Pedersen, H. S., Junior, G. A. D. O., Alexandre, P., Razza, E. M., Callesen, H., Hyttel, P., Nogueira, M. F. G., Ferraz, J. B. S. & Kadarmideen, H. N., 2017, In: Animal Reproduction. 14, 3, p. 507-513 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Basic and practical aspects of pregnancy establishment in cattle

    Pedersen, H. S., Mazzoni, G., Stroebech, L., Kadarmideen, H. N., Hyttel, P. & Callesen, H., 2017, In: Animal Reproduction. 14, 3, p. 581-588 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Characterization of energy and neurotransmitter metabolism in cortical glutamatergic neurons derived from human induced pluripotent stem cells: A novel approach to study metabolism in human neurons

    Aldana, Blanca, Zhang, Y., Lihme, M. F., Bak, Lasse Kristoffer, Nielsen, Jørgen Erik, Holst, B., Hyttel, P., Freude, Kristine & Waagepetersen, Helle S., 2017, In: Neurochemistry International. 106, p. 48-61

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Comparison of 2D and 3D neural induction methods for the generation of neural progenitor cells from human induced pluripotent stem cells

    Chandrasekaran, Abinaya, Avci, H., Ochalek, A., Rosingh, L., Molnar, K., Laszlo, L., Bellak, T., Teglasi, A., Pesti, K., Mike, A., Phanthong, P., Biro, O., Hall, Vanessa Jane, Kitiyanant, N., Krause, K., Kobolak, J. & Dinnyés, A., 2017, In: Stem Cell Research. 25, p. 139-151

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    DOT1L inhibitor improves early development of porcine somatic cell nuclear transfer embryos

    Tao, J., Zhang, Y., Zuo, X., Hong, R., Li, H., Liu, X., Huang, W., Cao, Z. & Zhang, Y., 2017, In: PloS one. 12, 6, 12 p., e0179436.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Evaluation of porcine stem cell competence for somatic cell nuclear transfer and production of cloned animals

    Secher, Jan Bojsen-Møller, Liu, Y., Petkov, S. G., Li, D., Hall, Vanessa Jane, Schmidt, M., Callesen, H., Freude, Kristine & Hyttel, P., 2017, In: Animal Reproduction Science. 178, p. 40-49

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    G protein-mediated signaling in the myogenic response – role of Rho-kinase and aging

    Björling, K., Joseph, P. D., Egebjerg, K., Hansen, J. L., Salomonsson, M. & Jensen, Lars Jørn, 2017, In: Journal of Vascular Research. 54, S2, p. 9 1 p., 8.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  28. Published

    Heteromeric Slick/Slack K+ channels show graded sensitivity to cell volume changes

    Tejada, M. A., Hashem, N., Callø, Kirstine & Klærke, Dan Arne, 2017, In: PLOS ONE. 12, 2, 11 p., e0169914.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Identification of SSEA-1 expressing enhanced reprogramming (SEER) cells in porcine embryonic fibroblasts

    Li, D., Secher, Jan Bojsen-Møller, Juhl, M., Mashayekhi-Nezamabadi, K., Nielsen, T. T., Holst, B., Hyttel, P., Freude, Kristine & Hall, Vanessa Jane, 2017, In: Cell Cycle. 16, 11, p. 1070-1084

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Identification of potential biomarkers in donor cows for in vitro embryo production by granulosa cell transcriptomics

    Mazzoni, G., Salleh, S. M., Freude, Kristine, Pedersen, H. S., Stroebech, L., Callesen, H., Hyttel, P. & Kadarmideen, H. N., 2017, In: PLOS ONE. 12, 4, 27 p., e0175464.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    In vitro production of bovine embryos: Cumulus/granulosa cell gene expression patterns point to early atresia as beneficial for oocyte competence

    Mazzoni, G., Razza, E., Pedersen, H. S., Secher, Jan Bojsen-Møller, Kadarmideen, H. N., Callesen, H., Stroebech, L., Freude, Kristine & Hyttel, P., 2017, In: Animal Reproduction. 14, 3, p. 482-489 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Intrauterine inoculation of minipigs with Chlamydia trachomatis during diestrus establishes a longer lasting infection compared to vaginal inoculation during estrus

    Lorenzen, E., Follmann, F., Secher, Jan Bojsen-Møller, Goericke-Pesch, S. K., Hansen, M. S., Zakariassen, H., Olsen, A. W., Andersen, P., Jungersen, G. & Agerholm, Jørgen Steen, 2017, In: Microbes and Infection. 19, 6, p. 334-342

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Mitochondrial Spare Respiratory Capacity Is Negatively Correlated with Nuclear Reprogramming Efficiency

    Yan, Z., Al-Saaidi, R. A., Fernandez Guerra, P., Freude, Kristine, Olsen, R. K. J., Jensen, U. B., Gregersen, N., Hyttel, P., Bolund, L., Aagaard, L., Bross, P. & Luo, Y., 2017, In: Stem Cells and Development. 26, 3, p. 166-176

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Modeling neurodegenerative diseases with patient-derived induced pluripotent cells: Possibilities and challenges

    Poon, A., Zhang, Y., Chandrasekaran, Abinaya, Phanthong, P., Schmid, B., Nielsen, T. T. & Freude, Kristine, 2017, In: New Biotechnology. 39, Part B, p. 190-198

    Research output: Contribution to journal › Review › Research › peer-review

  35. Published

    Online Radiology Reporting with Peer Review as a Learning and Feedback Tool in Radiology; Implementation, Validity, and Student Impressions

    McEvoy, Fintan, Shen, N. W., Nielsen, Dorte Hald, Buelund, Lene Elisabeth & Holm, Peter, 2017, In: Journal of Digital Imaging. 30, 1, p. 78-85 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Optimal doses of EGF and GDNF act as biological response modifiers to improve porcine oocyte maturation and quality

    Valleh, M. V., Zandi, N. K., Rasmussen, M. A. & Hyttel, P., 2017, In: Zygote. 25, 4, p. 423-433 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Patient iPSC-derived neurons for disease modeling of frontotemporal dementia with mutation in CHMP2B

    Zhang, Y., Schmid, B., Qas Younan, N. K., Rasmussen, M. A., Garcia, B. I. A., Agger, M., Callø, K., Stummann, T. C., Larsen, H. M., Nielsen, T. T., Huang, J., Xu, F., Liu, X., Bolund, L., Meyer, M., Bak, L. K., Waagepetersen, H. S., Luo, Y., Nielsen, J. E., Consortium, T. FRA. & 4 others, Holst, B., Clausen, C., Hyttel, P. & Freude, Kristine, 2017, In: Stem Cell Reports. 8, 3, p. 648-658

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Paving the way towards complex blood-brain barrier models using pluripotent stem cells

    Lauschke, K., Frederiksen, L. & Hall, Vanessa Jane, 2017, In: Stem Cells and Development. 26, 12, p. 857-874

    Research output: Contribution to journal › Review › Research › peer-review

  39. Published

    RNA-Seq transcriptomics and pathway analyses reveal potential regulatory genes and molecular mechanisms in high- and low-residual feed intake in Nordic dairy cattle

    Salleh, M. S., Mazzoni, G., Höglund, J. K., Olijhoek, D. W., Lund, P., Løvendahl, P. & Kadarmideen, H. N., 2017, In: BMC Genomics. 18, 1, 17 p., 258.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Single-Channel Recordings of K+ Channels Expressed in Saccharomyces Cerevisiae

    Tejada, M. D. L. A., Molbaek, K., Cazimi, H., Ellekvist, P., Callø, Kirstine, Nielsen, C. H., Pedersen, Per Amstrup & Klærke, Dan Arne, 2017, In: Biophysical Journal. 112, 3, Suppl. 1, p. 406A 1 p., 2002-Pos Board B322.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  41. Published

    Systematic in vitro and in vivo characterization of Leukemia-inhibiting factor- and Fibroblast growth factor-derived porcine induced pluripotent stem cells

    Secher, J. O. B., Ceylan, A., Mazzoni, G., Mashayekhi-Nezamabadi, K., Li, T., Muenthaisong, S., Nielsen, T., Li, D., Li, S., Petkov, S. G., Cirera Salicio, S., Luo, Y., Thombs, L., Kadarmideen, H., Dinnyés, A., Bolund, L., Roelen, B. A., Schmidt, M., Callesen, H., Hyttel, P. & 1 others, Freude, Kristine, 2017, In: Molecular Reproduction and Development. 84, 3, p. 229-245

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    T-type Ca(2+) channels and Autoregulation of Local Blood Flow

    Jensen, Lars Jørn, Nielsen, Morten Schak, Salomonsson, M. & Sorensen, Charlotte Mehlin, 2017, In: Channels (Austin). 11, 3, p. 183-195 13 p.

    Research output: Contribution to journal › Review › Research › peer-review

  43. Published

    The Application of Acoustic Myography in Canine Muscle Function and Performance Testing

    Fenger, C. & Harrison, Adrian Paul, 2017, In: SOJ Veterinary Sciences. 3, 2, p. 1-3 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    The Use of Acoustic MyoGraphy as a Measure of Training Effects in Athletes- A 10 Month Case Study of a BMX Rider

    Bartels, E. M., Harder, A., Heide, K. S., Pingel, Jessica, Harrison, Adrian Paul & Andersen, I. T., 2017, In: Annals of Sports Medicine and Research. 4, 1, 6 p., 1101.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    The effect of diet and exercise on plasma metabolite and hormone concentrations in horses measured before and after exercise

    Jensen, R. B., Blache, D., Bach Knudsen, K. E., Austbø, D. & Tauson, Anne-Helene, 2017, In: Comparative Exercise Physiology. 13, 2, p. 97-104 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Wip1-dependent modulation of macrophage migration and phagocytosis

    Tang, Y., Pan, B., Zhou, X., Xiong, K., Gao, Q., Huang, L., Xia, Y., Shen, M., Yang, S., Liu, H., Tan, T., Ma, J., Xu, X., Mu, Y. & Li, K., 2017, In: Redox Biology. 13, p. 665-673 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. 2016
  48. Published

    Initial Attempts of Development and Characterization of an In Vitro Blood Brain Barrier Model Derived from Human Pluripotent Stem Cells

    Goldeman, C., Saaby, L., Hall, Vanessa Jane, Hyttel, P. & Larsen, Birger Brodin, 8 Dec 2016. 1 p.

    Research output: Contribution to conference › Poster › Research › peer-review

  49. Published

    Generation of an isogenic, gene-corrected iPSC line from a symptomatic 57-year-old female patient with frontotemporal dementia caused by a P301L mutation in the microtubule associated protein tau (MAPT) gene

    Nimsanor, N., Kitiyanant, N., Poulsen, U., Rasmussen, M. A., Clausen, C., Mau-Holzmann, U. A., Nielsen, Jørgen Erik, Nielsen, T. T., Hyttel, P., Holst, B. & Schmid, B., Nov 2016, In: Stem Cell Research. 17, 3, p. 556-559 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Generation of an isogenic, gene-corrected iPSC line from a symptomatic 59-year-old female patient with frontotemporal dementia caused by an R406W mutation in the microtubule associated protein tau (MAPT) gene

    Nimsanor, N., Poulsen, U., Rasmussen, M. A., Clausen, C., Mau-Holzmann, U. A., Nielsen, Jørgen Erik, Nielsen, T. T., Hyttel, P., Holst, B. & Schmid, B., Nov 2016, In: Stem Cell Research. 17, 3, p. 576-579 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Induced pluripotent stem cells (iPSCs) derived from a symptomatic carrier of a S305I mutation in the microtubule-associated protein tau (MAPT)-gene causing frontotemporal dementia

    Nimsanor, N., Jørring, I., Rasmussen, M. A., Clausen, C., Mau-Holzmann, U. A., Kitiyanant, N., Nielsen, Jørgen Erik, Nielsen, T. T., Hyttel, P., Holst, B. & Schmid, B., Nov 2016, In: Stem Cell Research. 17, 3, p. 564-567 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Systems Biology and Stem Cell Pluripotency: Revisiting the Discovery of Induced Pluripotent Stem Cell

    Mashayekhi, K., Hall, Vanessa Jane, Freude, Kristine, Høffding, M. K., Labusca, L. & Hyttel, P., 29 Oct 2016, Systems Biology in Animal Production and Health. Kadarmideen, H. N. (ed.). 1 ed. Springer, Vol. 2. p. 127-154 28 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

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