In Mexico, information on goat production is scarce and documenting goat production challenges and future perspectives could be of great value, not only for Latin America, but also for international players—including those from farms, industry, and academia. Therefore, the objective of this review is to provide current knowledge on goat production systems in Mexico and discuss current challenges and future perspectives for this animal production sector. In Mexico, more than 70% of goats are produced under extensive production systems in arid and semi-arid areas and roughly 25% are produced in intensive or semi-intensive systems. Main breeds are French Alpine, Saanen, Toggenburg, LaMancha, Nubian, Boer, and their crosses. The main challenges are correlated at different levels, where economic, social, and environmental issues are mixed and are closely associated with goat health and welfare. Newly available farming technologies could be an option that should be explored. Mexican goat farming systems will need to look at the animal, social, and environmental factors to promote sustainable production systems