vanO, a new glycopeptide resistance operon in environmental Rhodococcus equi isolates
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vanO, a new glycopeptide resistance operon in environmental Rhodococcus equi isolates. / Gudeta, Dereje Dadi; Moodley, Arshnee; Bortolaia, Valeria; Guardabassi, Luca.
I: Antimicrobial Agents and Chemotherapy, Bind 58, Nr. 3, 2014, s. 1768-1770.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - vanO, a new glycopeptide resistance operon in environmental Rhodococcus equi isolates
AU - Gudeta, Dereje Dadi
AU - Moodley, Arshnee
AU - Bortolaia, Valeria
AU - Guardabassi, Luca
PY - 2014
Y1 - 2014
N2 - We describe sequence and gene organization of a new glycopeptide resistance operon (vanO) in Rhodococcus equi from soil. The vanO operon has low homology to enterococccal van operons and harbors a vanHOX cluster transcribed in opposite direction to the vanS-vanR regulatory system and comprised between three open reading frames with unknown function. This finding has clinical interest since glycopeptides are used to treat R. equi infections and resistance has been reported in clinical isolates.
AB - We describe sequence and gene organization of a new glycopeptide resistance operon (vanO) in Rhodococcus equi from soil. The vanO operon has low homology to enterococccal van operons and harbors a vanHOX cluster transcribed in opposite direction to the vanS-vanR regulatory system and comprised between three open reading frames with unknown function. This finding has clinical interest since glycopeptides are used to treat R. equi infections and resistance has been reported in clinical isolates.
U2 - 10.1128/AAC.01880-13
DO - 10.1128/AAC.01880-13
M3 - Journal article
C2 - 24342631
VL - 58
SP - 1768
EP - 1770
JO - Antimicrobial Agents and Chemotherapy
JF - Antimicrobial Agents and Chemotherapy
SN - 0066-4804
IS - 3
ER -
ID: 94069068