Effect of praziquantel treatment of Schistosoma mansoni during pregnancy on immune responses to schistosome antigens among the offspring: results of a randomised, placebo-controlled trial

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Standard

Effect of praziquantel treatment of Schistosoma mansoni during pregnancy on immune responses to schistosome antigens among the offspring : results of a randomised, placebo-controlled trial. / Tweyongyere, Robert; Mawa, Patrice A.; Kihembo, Macklyn; Jones, Frances M.; Webb, Emily L.; Cose, Stephen; Dunne, David W.; Vennervald, Birgitte J; Elliott, Alison M.

I: B M C Infectious Diseases, Bind 11, Nr. 234, 2011.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Tweyongyere, R, Mawa, PA, Kihembo, M, Jones, FM, Webb, EL, Cose, S, Dunne, DW, Vennervald, BJ & Elliott, AM 2011, 'Effect of praziquantel treatment of Schistosoma mansoni during pregnancy on immune responses to schistosome antigens among the offspring: results of a randomised, placebo-controlled trial', B M C Infectious Diseases, bind 11, nr. 234. https://doi.org/10.1186/1471-2334-11-234

APA

Tweyongyere, R., Mawa, P. A., Kihembo, M., Jones, F. M., Webb, E. L., Cose, S., Dunne, D. W., Vennervald, B. J., & Elliott, A. M. (2011). Effect of praziquantel treatment of Schistosoma mansoni during pregnancy on immune responses to schistosome antigens among the offspring: results of a randomised, placebo-controlled trial. B M C Infectious Diseases, 11(234). https://doi.org/10.1186/1471-2334-11-234

Vancouver

Tweyongyere R, Mawa PA, Kihembo M, Jones FM, Webb EL, Cose S o.a. Effect of praziquantel treatment of Schistosoma mansoni during pregnancy on immune responses to schistosome antigens among the offspring: results of a randomised, placebo-controlled trial. B M C Infectious Diseases. 2011;11(234). https://doi.org/10.1186/1471-2334-11-234

Author

Tweyongyere, Robert ; Mawa, Patrice A. ; Kihembo, Macklyn ; Jones, Frances M. ; Webb, Emily L. ; Cose, Stephen ; Dunne, David W. ; Vennervald, Birgitte J ; Elliott, Alison M. / Effect of praziquantel treatment of Schistosoma mansoni during pregnancy on immune responses to schistosome antigens among the offspring : results of a randomised, placebo-controlled trial. I: B M C Infectious Diseases. 2011 ; Bind 11, Nr. 234.

Bibtex

@article{91d65e0f411d4c9097ee7d37d8b6f381,
title = "Effect of praziquantel treatment of Schistosoma mansoni during pregnancy on immune responses to schistosome antigens among the offspring: results of a randomised, placebo-controlled trial",
abstract = "Offspring of women with schistosomiasis may exhibit immune responsiveness to schistosomes due to in utero sensitisation or trans-placental transfer of antibodies. Praziquantel treatment during pregnancy boosts maternal immune responses to schistosome antigens and reduces worm burden. Effects of praziquantel treatment during pregnancy on responses among offspring are unknown.",
keywords = "Animals, Antibodies, Protozoan, Antigens, Protozoan, Antiprotozoal Agents, Cytokines, Female, Humans, Immunity, Maternally-Acquired, Infant, Infant, Newborn, Leukocytes, Mononuclear, Placebos, Praziquantel, Pregnancy, Pregnancy Complications, Parasitic, Schistosoma mansoni, Schistosomiasis mansoni, Treatment Outcome, Uganda",
author = "Robert Tweyongyere and Mawa, {Patrice A.} and Macklyn Kihembo and Jones, {Frances M.} and Webb, {Emily L.} and Stephen Cose and Dunne, {David W.} and Vennervald, {Birgitte J} and Elliott, {Alison M.}",
year = "2011",
doi = "10.1186/1471-2334-11-234",
language = "English",
volume = "11",
journal = "B M C Infectious Diseases",
issn = "1471-2334",
publisher = "BioMed Central Ltd.",
number = "234",

}

RIS

TY - JOUR

T1 - Effect of praziquantel treatment of Schistosoma mansoni during pregnancy on immune responses to schistosome antigens among the offspring

T2 - results of a randomised, placebo-controlled trial

AU - Tweyongyere, Robert

AU - Mawa, Patrice A.

AU - Kihembo, Macklyn

AU - Jones, Frances M.

AU - Webb, Emily L.

AU - Cose, Stephen

AU - Dunne, David W.

AU - Vennervald, Birgitte J

AU - Elliott, Alison M.

PY - 2011

Y1 - 2011

N2 - Offspring of women with schistosomiasis may exhibit immune responsiveness to schistosomes due to in utero sensitisation or trans-placental transfer of antibodies. Praziquantel treatment during pregnancy boosts maternal immune responses to schistosome antigens and reduces worm burden. Effects of praziquantel treatment during pregnancy on responses among offspring are unknown.

AB - Offspring of women with schistosomiasis may exhibit immune responsiveness to schistosomes due to in utero sensitisation or trans-placental transfer of antibodies. Praziquantel treatment during pregnancy boosts maternal immune responses to schistosome antigens and reduces worm burden. Effects of praziquantel treatment during pregnancy on responses among offspring are unknown.

KW - Animals

KW - Antibodies, Protozoan

KW - Antigens, Protozoan

KW - Antiprotozoal Agents

KW - Cytokines

KW - Female

KW - Humans

KW - Immunity, Maternally-Acquired

KW - Infant

KW - Infant, Newborn

KW - Leukocytes, Mononuclear

KW - Placebos

KW - Praziquantel

KW - Pregnancy

KW - Pregnancy Complications, Parasitic

KW - Schistosoma mansoni

KW - Schistosomiasis mansoni

KW - Treatment Outcome

KW - Uganda

U2 - 10.1186/1471-2334-11-234

DO - 10.1186/1471-2334-11-234

M3 - Journal article

C2 - 21888656

VL - 11

JO - B M C Infectious Diseases

JF - B M C Infectious Diseases

SN - 1471-2334

IS - 234

ER -

ID: 36091168