Effect of praziquantel treatment of Schistosoma mansoni during pregnancy on immune responses to schistosome antigens among the offspring: results of a randomised, placebo-controlled trial

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

  • Robert Tweyongyere
  • Patrice A. Mawa
  • Macklyn Kihembo
  • Frances M. Jones
  • Emily L. Webb
  • Stephen Cose
  • David W. Dunne
  • Vennervald, Birgitte J
  • Alison M. Elliott
Offspring of women with schistosomiasis may exhibit immune responsiveness to schistosomes due to in utero sensitisation or trans-placental transfer of antibodies. Praziquantel treatment during pregnancy boosts maternal immune responses to schistosome antigens and reduces worm burden. Effects of praziquantel treatment during pregnancy on responses among offspring are unknown.
OriginalsprogEngelsk
TidsskriftB M C Infectious Diseases
Vol/bind11
Udgave nummer234
Antal sider13
ISSN1471-2334
DOI
StatusUdgivet - 2011

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