Expression of nitric oxide synthases and effects of L-arginine and L-NMMA on nitric oxide production and fluid transport in collagenous colitis
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Standard
Expression of nitric oxide synthases and effects of L-arginine and L-NMMA on nitric oxide production and fluid transport in collagenous colitis. / Perner, A; Andresen, Lars; Normark, M; Fischer-Hansen, B; Sørensen, S; Eugen-Olsen, J; Rask-Madsen, J.
I: Gut, Bind 49, Nr. 3, 2001, s. 387-94.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Expression of nitric oxide synthases and effects of L-arginine and L-NMMA on nitric oxide production and fluid transport in collagenous colitis
AU - Perner, A
AU - Andresen, Lars
AU - Normark, M
AU - Fischer-Hansen, B
AU - Sørensen, S
AU - Eugen-Olsen, J
AU - Rask-Madsen, J
PY - 2001
Y1 - 2001
N2 - Luminal nitric oxide (NO) is greatly increased in the colon of patients with collagenous and ulcerative colitis. To define the source and consequence of enhanced NO production we have studied expression of NO synthase (NOS) isoforms and nitrotyrosine in mucosal biopsies from these patients. In addition, effects on colonic fluid transfer caused by manipulating the substrate of NOS were studied in patients with collagenous colitis.
AB - Luminal nitric oxide (NO) is greatly increased in the colon of patients with collagenous and ulcerative colitis. To define the source and consequence of enhanced NO production we have studied expression of NO synthase (NOS) isoforms and nitrotyrosine in mucosal biopsies from these patients. In addition, effects on colonic fluid transfer caused by manipulating the substrate of NOS were studied in patients with collagenous colitis.
KW - Adult
KW - Aged
KW - Arginine
KW - Blotting, Western
KW - Body Fluids
KW - Case-Control Studies
KW - Colitis, Ulcerative
KW - Confidence Intervals
KW - Female
KW - Humans
KW - Intestinal Absorption
KW - Male
KW - Middle Aged
KW - Nitric Oxide
KW - Nitric Oxide Synthase
KW - Nitric Oxide Synthase Type I
KW - Nitric Oxide Synthase Type II
KW - Nitric Oxide Synthase Type III
KW - Statistics, Nonparametric
KW - Tyrosine
KW - Up-Regulation
KW - omega-N-Methylarginine
M3 - Journal article
C2 - 11511561
VL - 49
SP - 387
EP - 394
JO - Gut
JF - Gut
SN - 0017-5749
IS - 3
ER -
ID: 35922714