Copresence of tet(K) and tet(M) in Livestock-Associated Methicillin-Resistant Staphylococcus aureus Clonal Complex 398 Is Associated with Increased Fitness during Exposure to Sublethal Concentrations of Tetracycline

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Standard

Copresence of tet(K) and tet(M) in Livestock-Associated Methicillin-Resistant Staphylococcus aureus Clonal Complex 398 Is Associated with Increased Fitness during Exposure to Sublethal Concentrations of Tetracycline. / Larsen, Jesper; Clasen, Julie; Hansen, Julie Elvekjær; Paulander, Wilhelm; Petersen, Andreas; Larsen, Anders Rhod; Frees, Dorte.

I: Antimicrobial Agents and Chemotherapy, Bind 60, Nr. 7, 07.2016, s. 4401-4403.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Larsen, J, Clasen, J, Hansen, JE, Paulander, W, Petersen, A, Larsen, AR & Frees, D 2016, 'Copresence of tet(K) and tet(M) in Livestock-Associated Methicillin-Resistant Staphylococcus aureus Clonal Complex 398 Is Associated with Increased Fitness during Exposure to Sublethal Concentrations of Tetracycline', Antimicrobial Agents and Chemotherapy, bind 60, nr. 7, s. 4401-4403. https://doi.org/10.1128/AAC.00426-16

APA

Larsen, J., Clasen, J., Hansen, J. E., Paulander, W., Petersen, A., Larsen, A. R., & Frees, D. (2016). Copresence of tet(K) and tet(M) in Livestock-Associated Methicillin-Resistant Staphylococcus aureus Clonal Complex 398 Is Associated with Increased Fitness during Exposure to Sublethal Concentrations of Tetracycline. Antimicrobial Agents and Chemotherapy, 60(7), 4401-4403. https://doi.org/10.1128/AAC.00426-16

Vancouver

Larsen J, Clasen J, Hansen JE, Paulander W, Petersen A, Larsen AR o.a. Copresence of tet(K) and tet(M) in Livestock-Associated Methicillin-Resistant Staphylococcus aureus Clonal Complex 398 Is Associated with Increased Fitness during Exposure to Sublethal Concentrations of Tetracycline. Antimicrobial Agents and Chemotherapy. 2016 jul.;60(7):4401-4403. https://doi.org/10.1128/AAC.00426-16

Author

Larsen, Jesper ; Clasen, Julie ; Hansen, Julie Elvekjær ; Paulander, Wilhelm ; Petersen, Andreas ; Larsen, Anders Rhod ; Frees, Dorte. / Copresence of tet(K) and tet(M) in Livestock-Associated Methicillin-Resistant Staphylococcus aureus Clonal Complex 398 Is Associated with Increased Fitness during Exposure to Sublethal Concentrations of Tetracycline. I: Antimicrobial Agents and Chemotherapy. 2016 ; Bind 60, Nr. 7. s. 4401-4403.

Bibtex

@article{47379723eb904c779307dc1dccb43fee,
title = "Copresence of tet(K) and tet(M) in Livestock-Associated Methicillin-Resistant Staphylococcus aureus Clonal Complex 398 Is Associated with Increased Fitness during Exposure to Sublethal Concentrations of Tetracycline",
abstract = "The tetracycline resistance gene tet(K) was shown to be integrated within the predominant staphylococcal cassette chromosome mec (SCCmec) element of Danish livestock-associated methicillin-resistant Staphylococcus aureus CC398 (LA-MRSA CC398). These LA-MRSA CC398 isolates already possessed tet(M), but the acquisition of tet(K) significantly improved their fitness at sublethal concentrations of tetracycline. Because tet(K) is genetically linked to SCCmec, the use of tetracycline in food animals may have contributed to the successful spread of LA-MRSA CC398.",
author = "Jesper Larsen and Julie Clasen and Hansen, {Julie Elvekj{\ae}r} and Wilhelm Paulander and Andreas Petersen and Larsen, {Anders Rhod} and Dorte Frees",
year = "2016",
month = jul,
doi = "10.1128/AAC.00426-16",
language = "English",
volume = "60",
pages = "4401--4403",
journal = "Antimicrobial Agents and Chemotherapy",
issn = "0066-4804",
publisher = "American Society for Microbiology",
number = "7",

}

RIS

TY - JOUR

T1 - Copresence of tet(K) and tet(M) in Livestock-Associated Methicillin-Resistant Staphylococcus aureus Clonal Complex 398 Is Associated with Increased Fitness during Exposure to Sublethal Concentrations of Tetracycline

AU - Larsen, Jesper

AU - Clasen, Julie

AU - Hansen, Julie Elvekjær

AU - Paulander, Wilhelm

AU - Petersen, Andreas

AU - Larsen, Anders Rhod

AU - Frees, Dorte

PY - 2016/7

Y1 - 2016/7

N2 - The tetracycline resistance gene tet(K) was shown to be integrated within the predominant staphylococcal cassette chromosome mec (SCCmec) element of Danish livestock-associated methicillin-resistant Staphylococcus aureus CC398 (LA-MRSA CC398). These LA-MRSA CC398 isolates already possessed tet(M), but the acquisition of tet(K) significantly improved their fitness at sublethal concentrations of tetracycline. Because tet(K) is genetically linked to SCCmec, the use of tetracycline in food animals may have contributed to the successful spread of LA-MRSA CC398.

AB - The tetracycline resistance gene tet(K) was shown to be integrated within the predominant staphylococcal cassette chromosome mec (SCCmec) element of Danish livestock-associated methicillin-resistant Staphylococcus aureus CC398 (LA-MRSA CC398). These LA-MRSA CC398 isolates already possessed tet(M), but the acquisition of tet(K) significantly improved their fitness at sublethal concentrations of tetracycline. Because tet(K) is genetically linked to SCCmec, the use of tetracycline in food animals may have contributed to the successful spread of LA-MRSA CC398.

U2 - 10.1128/AAC.00426-16

DO - 10.1128/AAC.00426-16

M3 - Journal article

C2 - 27161637

VL - 60

SP - 4401

EP - 4403

JO - Antimicrobial Agents and Chemotherapy

JF - Antimicrobial Agents and Chemotherapy

SN - 0066-4804

IS - 7

ER -

ID: 165398919