Learning From Mistakes: The Role of Phages in Pandemics
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Learning From Mistakes : The Role of Phages in Pandemics. / Alsaadi, Ahlam; Beamud, Beatriz; Easwaran, Maheswaran; Abdelrahman, Fatma; El-Shibiny, Ayman; Alghoribi, Majed F.; Domingo-Calap, Pilar.
I: Frontiers in Microbiology, Bind 12, 653107, 2021.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Learning From Mistakes
T2 - The Role of Phages in Pandemics
AU - Alsaadi, Ahlam
AU - Beamud, Beatriz
AU - Easwaran, Maheswaran
AU - Abdelrahman, Fatma
AU - El-Shibiny, Ayman
AU - Alghoribi, Majed F.
AU - Domingo-Calap, Pilar
PY - 2021
Y1 - 2021
N2 - The misuse of antibiotics is leading to the emergence of multidrug-resistant (MDR) bacteria, and in the absence of available treatments, this has become a major global threat. In the middle of the recent severe acute respiratory coronavirus 2 (SARS-CoV-2) pandemic, which has challenged the whole world, the emergence of MDR bacteria is increasing due to prophylactic administration of antibiotics to intensive care unit patients to prevent secondary bacterial infections. This is just an example underscoring the need to seek alternative treatments against MDR bacteria. To this end, phage therapy has been proposed as a promising tool. However, further research in the field is mandatory to assure safety protocols and to develop appropriate regulations for its use in clinics. This requires investing more in such non-conventional or alternative therapeutic approaches, to develop new treatment regimens capable of reducing the emergence of MDR and preventing future global public health concerns that could lead to incalculable human and economic losses.
AB - The misuse of antibiotics is leading to the emergence of multidrug-resistant (MDR) bacteria, and in the absence of available treatments, this has become a major global threat. In the middle of the recent severe acute respiratory coronavirus 2 (SARS-CoV-2) pandemic, which has challenged the whole world, the emergence of MDR bacteria is increasing due to prophylactic administration of antibiotics to intensive care unit patients to prevent secondary bacterial infections. This is just an example underscoring the need to seek alternative treatments against MDR bacteria. To this end, phage therapy has been proposed as a promising tool. However, further research in the field is mandatory to assure safety protocols and to develop appropriate regulations for its use in clinics. This requires investing more in such non-conventional or alternative therapeutic approaches, to develop new treatment regimens capable of reducing the emergence of MDR and preventing future global public health concerns that could lead to incalculable human and economic losses.
KW - antibiotic resistance
KW - emergent pathogen
KW - multidrug-resistant bacteria
KW - phage therapy
KW - public health
U2 - 10.3389/fmicb.2021.653107
DO - 10.3389/fmicb.2021.653107
M3 - Journal article
C2 - 33815346
AN - SCOPUS:85103479108
VL - 12
JO - Frontiers in Microbiology
JF - Frontiers in Microbiology
SN - 1664-302X
M1 - 653107
ER -
ID: 259880712