TY - JOUR

T1 - Wearing occlusive gloves increases the density of staphylococcus aureus in patients with hand eczema

AU - Nørreslet, Line Brok

AU - Edslev, Sofie Marie

AU - Flachs, Esben Meulengracht

AU - Ebbehøj, Niels Erik

AU - Andersen, Paal Skytt

AU - Agner, Tove

N1 - Funding Information: This work was supported by The Danish Working Environment Fund (grant number 20185100823); Augustinusfonden; and Aage Bangs Fond. The funding sources were not involved in this study, including the study design; the collection, analysis and interpretation of data; the writing of the paper; or the submission process. Publisher Copyright: © 2021, Medical Journals/Acta D-V. All rights reserved.

PY - 2021

Y1 - 2021

N2 - Hand eczema is frequently colonized with Staphylococcus aureus. Some patients with hand eczema wear occlusive gloves regularly; however, the effect of this on the density of S. aureus is unexplored. The aim of this study is to examine the effect of occlusive gloves on the density of S. aureus sampled from the hands of patients with hand eczema. In an experimental set-up, patients with moderate-to-severe hand eczema wore an occlusive glove on one hand for 4 h with a 30-min break. Bacterial swabs were collected from the most severe eczema lesion on the hand before and immediately after glove exposure. S. aureus colony-forming units were counted and log-transformations used for comparison of before- and after-values. Among 30 patients, 19 (63%) were colonized with S. aureus. After glove occlusion S. aureus colony-forming units increased by a factor of 1.72 (p < 0.01). In conclusion, the density of sampled S. aureus on eczematous skin after prolonged wearing of occlusive gloves is greatly increased.

AB - Hand eczema is frequently colonized with Staphylococcus aureus. Some patients with hand eczema wear occlusive gloves regularly; however, the effect of this on the density of S. aureus is unexplored. The aim of this study is to examine the effect of occlusive gloves on the density of S. aureus sampled from the hands of patients with hand eczema. In an experimental set-up, patients with moderate-to-severe hand eczema wore an occlusive glove on one hand for 4 h with a 30-min break. Bacterial swabs were collected from the most severe eczema lesion on the hand before and immediately after glove exposure. S. aureus colony-forming units were counted and log-transformations used for comparison of before- and after-values. Among 30 patients, 19 (63%) were colonized with S. aureus. After glove occlusion S. aureus colony-forming units increased by a factor of 1.72 (p < 0.01). In conclusion, the density of sampled S. aureus on eczematous skin after prolonged wearing of occlusive gloves is greatly increased.

KW - Alcohol-based hand rub

KW - Bacteria

KW - Hand eczema

KW - Infection prevention

KW - Occlusive gloves

KW - Staphylococcus aureus

U2 - 10.2340/00015555-3866

DO - 10.2340/00015555-3866

M3 - Journal article

C2 - 34219178

AN - SCOPUS:85114386001

VL - 101

JO - Acta Dermato-Venereologica

JF - Acta Dermato-Venereologica

SN - 0001-5555

IS - 8

M1 - adv00515

ER -