The molluscicidal activity of coumarins from Ethulia conyzoides and of dicumarol
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The molluscicidal activity of coumarins from Ethulia conyzoides and of dicumarol. / Kady, M M; Brimer, L; Furu, P; Lemmich, E; Nielsen, H M; Thiilborg, S T; Thastrup, Ole; Christensen, S B.
I: Planta Medica, Bind 58, Nr. 4, 1992, s. 334-7.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - The molluscicidal activity of coumarins from Ethulia conyzoides and of dicumarol
AU - Kady, M M
AU - Brimer, L
AU - Furu, P
AU - Lemmich, E
AU - Nielsen, H M
AU - Thiilborg, S T
AU - Thastrup, Ole
AU - Christensen, S B
PY - 1992
Y1 - 1992
N2 - The molluscicidal principles of Ethulia conyzoides were identified as ethuliacoumarin A (1) and isoethuliacoumarin A (2). Ethuliacoumarin A possessed an LC90 between 19 and 23.5 ppm depending on the age of the snail against Biomphalaria glabrata, and between 12 and 15 ppm against Bulinus truncatus. In addition, ethuliacoumarin A was found to be cercaricidal at 25 ppm and ovicidal. Ethuliacoumarin has the structural requirements considered essential for anticoagulant activity. Consequently the anticoagulant dicumarol (4) was tested and found to be molluscicidal in the range from 2.5 to 10 ppm. In contrast, the coumarin anticoagulant warfarin (3) did not show molluscicidal activity.
AB - The molluscicidal principles of Ethulia conyzoides were identified as ethuliacoumarin A (1) and isoethuliacoumarin A (2). Ethuliacoumarin A possessed an LC90 between 19 and 23.5 ppm depending on the age of the snail against Biomphalaria glabrata, and between 12 and 15 ppm against Bulinus truncatus. In addition, ethuliacoumarin A was found to be cercaricidal at 25 ppm and ovicidal. Ethuliacoumarin has the structural requirements considered essential for anticoagulant activity. Consequently the anticoagulant dicumarol (4) was tested and found to be molluscicidal in the range from 2.5 to 10 ppm. In contrast, the coumarin anticoagulant warfarin (3) did not show molluscicidal activity.
KW - Animals
KW - Anticoagulants
KW - Biomphalaria
KW - Bulinus
KW - Coumarins
KW - Molluscacides
KW - Plants, Medicinal
U2 - 10.1055/s-2006-961479
DO - 10.1055/s-2006-961479
M3 - Journal article
C2 - 1438593
VL - 58
SP - 334
EP - 337
JO - Planta Medica
JF - Planta Medica
SN - 0032-0943
IS - 4
ER -
ID: 43349489